MS Paint

[Gors]

It actually places pixels slightly off-centered; this difference makes it annoying to pick colors with the eye-dropper/single pixel placement. Unless there is some setting option I'm missing, all brush strokes are anti-aliased, and the pencil scribbles get some of their pixels eaten.

Right-clicking the color is far easier for a color you use with the right mouse button. I could get used to it, but meh.

Opening a image file with the new paint messes up the transparent color, so even if you set said color as transparent, it'll still act like it isn't. The only way around this is to repaint the background with another color and setting the new color as transparent.

I've tried color-replacing in 7paint before and I couldn't/don't remember if I succeeded, either way I still don't reccomend it for pixelling at all.