2D or 3D graphics ? For 2D, I use letterbox scaling or normal scaling with wide background and objects extended beyond layout borders so it's impossible to see black borders; and for 3D, I have 2 cameras (16:9 and 4: 3 with different field of view) that are actived depending of the phone screen.
But in general, you have to try on simulated or real devices.
But in general, you have to try on simulated or real devices.